Urinary 3-Methoxytyramine Is a Biomarker for MYC Activity in Patients With Neuroblastoma.
Iedan R N VerlyYvette A H MatserRené LeenRutger MeinsmaMarta FioccoJan KosterRichard VolckmannDilara Savci-HeijinkGiuliana CangemiSebastiano BarcoLinda J ValentijnGodelieve A M TytgatAndré B P van KuilenburgPublished in: JCO precision oncology (2022)
Elevated urinary 3MT is a promising biomarker for poor prognosis and reflects increased MYC activity in the tumor. Therefore, urinary 3MT levels should be measured at diagnosis and may assist in assessing risk.