Photocatalytic redox-neutral α-C(sp 3 )-H pyridination of glycine derivatives and N -arylamines with cyanopyridines.

A photo-induced α-C(sp 3 )-H decyanative pyridination of N -arylglycine derivatives with cyanopyridines was developed. This reaction was performed under organic photocatalytic and redox-neutral conditions via a radical-radical cross-coupling process. Besides, the protocol was also suitable for the C(sp 3 )-H pyridination of N -aryl tetrahydroisoquinolines as well as benzylamines.