The tissue origin of human mesenchymal stem cells dictates their therapeutic efficacy on glucose and lipid metabolic disorders in type II diabetic mice.
Yinzhong MaLisha WangShilun YangDongyu LiuYi ZengLilong LinLinhui QiuJiahao LuJunlei ChangZhihuan LiPublished in: Stem cell research & therapy (2021)
Taken together, our results demonstrated that MSCs of different tissue origins can confer substantially different therapeutic efficacy in ameliorating glucose and lipid metabolic disorders in type II diabetes. MSCs with different therapeutic characteristics could be selected according to the purpose of the treatment in the future clinical practice.