Extracorporeal shock wave promotes activation of anterior cruciate ligament remnant cells and their paracrine regulation of bone marrow stromal cells' proliferation, migration, collagen synthesis, and differentiation.

Cheng-Chang LuShih-Hsiang ChouPo-Chih ShenPei-Hsi ChouMei-Ling HoYin-Chun Tien

Published in: Bone & joint research (2020)

ACL remnant cells modulated activity and differentiation of surrounding cells. The results indicated that ESW enhanced ACL remnant cells viability, proliferation, migration, and expression of collagen, TGF-β, VEGF, and paracrine regulation of BMSC proliferation, migration, collagen expression, and tenogenesis.Cite this article: Bone Joint Res 2020;9(8):458-468.

Keyphrases

induced apoptosis
cell cycle arrest
signaling pathway
bone marrow
poor prognosis
mesenchymal stem cells
long non coding rna
tissue engineering
pi k akt
body composition
bone loss