Vortex-assisted dispersive micro-solid-phase extraction using silica-supported Fe 2 O 3 -modified khat ( C atha edulis) biochar nanocomposite followed by GC-MS for the determination of organochlorine pesticides in juice samples.
Kero Assefa AgoAbera GureShimeles Addisu KitteJemere KochitoYerosan Buzayo BalchaPublished in: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes (2024)
In this paper, dispersive micro-solid phase extraction technique was developed for the purpose of extracting and preconcentrating organochlorine pesticide residues in juice samples before their separation and quantitative analysis by gas chromatography-mass spectrometry. A sorbent composed of a silica-supported Fe 2 O 3 -modified khat leftover biochar nanocomposite (SiO 2 -Fe 2 O 3 -KLBNC) was implemented in the process. To improve the dispersion of the sorbent in the solution, vortex mixer was employed. Experimental parameters influencing the performance of the method were optimized, and the optimal conditions were established. With these conditions, linear dynamic ranges ranged from 0.003 to 100.0 ng/mL were achieved, with a correlation coefficient (r 2 ) ≥ 0.9981. The limits of detection and quantification, determined by signal-to-noise ratios of 3 and 10, respectively, were found to be in the ranges of 0.001-0.006 ng/mL and 0.003-0.020 ng/mL. Intra- and inter-day precision, values ranging from 0.3-4.8% and 1.7-5.2% were obtained, respectively. The matrix-matched extraction recoveries demonstrated favorable outcomes, falling within the range of 83.4-108.3%. The utilization of khat leftover as an adsorbent in contemporary sample preparation methodologies offers a cost-effective alternative to the currently available, yet expensive, adsorbents. This renders it economically viable, particularly in resource-constrained regions, and is anticipated to witness widespread adoption in the coming future.
Keyphrases
- solid phase extraction
- gas chromatography mass spectrometry
- molecularly imprinted
- liquid chromatography
- gas chromatography
- high performance liquid chromatography
- liquid chromatography tandem mass spectrometry
- heavy metals
- risk assessment
- tandem mass spectrometry
- simultaneous determination
- sewage sludge
- ultra high performance liquid chromatography
- mass spectrometry
- anaerobic digestion
- high resolution mass spectrometry
- loop mediated isothermal amplification
- plant growth
- electronic health record
- air pollution
- current status
- adipose tissue
- computed tomography
- high resolution
- metabolic syndrome
- lactic acid
- community dwelling