Determinants of Circulating Soluble Leptin Receptor and Free Leptin Index in Indonesian Pre-Pubertal Obese Male Children: A Preliminary Cross-Sectional Study.

Aryono HendartoDimple G NagraniAnna MeilianaSudigdo SastroasmoroDamayanti R Sjarif

Published in: Pediatric gastroenterology, hepatology & nutrition (2020)

Leptin regulation in prepubertal obese male children is associated with body composition and dietary intake. Carbohydrate intake is useful for predicting CSLR. Lipid profiles and insulin resistance are not related to both CSLR and FLI. Treatment and prevention of leptin resistance in obese children should focus on reducing BMI, fat mass, and carbohydrate intake.

Keyphrases

body composition
adipose tissue
metabolic syndrome
insulin resistance
young adults
type diabetes
weight loss
obese patients
weight gain
body mass index
high fat diet
fatty acid
bariatric surgery
polycystic ovary syndrome
combination therapy