The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases.

Sylwia Szrok-Jurga Jacek TurynAreta HebanowskaJulian SwierczynskiAleksandra Czumaj Tomasz Sledzinski Ewa Stelmanska

Published in: International journal of molecular sciences (2023)

This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.

Keyphrases

fatty acid
resting state
white matter
functional connectivity
hydrogen peroxide
cerebral ischemia
nitric oxide