Exploring Pharmacological Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Traumatic Brain Injury via a Network Pharmacology Approach.

Yuanyuan ZhongJie-Kun Luo Tao TangPengfei LiTao LiuHanjin CuiYang Wang Zebing Huang

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

Our work successfully illuminates the "multicompounds, multitargets" therapeutic action of XFZYD in the treatment of TBI by network pharmacology with molecule docking method. The present work may provide valuable evidence for further clinical application of XFZYD as therapeutic strategy for TBI treatment.

Keyphrases

traumatic brain injury
combination therapy
small molecule
severe traumatic brain injury
molecular dynamics simulations
protein protein
replacement therapy
mild traumatic brain injury