The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma.

Go OmuraMizuo AndoYasuhiro EbiharaYuki SaitoKenya KobayashiOsamu FukuokaKen AkashiMasafumi YoshidaTakahiro AsakageTatsuya Yamasoba

Published in: BMC cancer (2017)

The TP53 mutation status correlated with poor prognosis in surgically treated HPSCC patients. Specifically, truncating mutations which were not detected by p53 immunohistochemistry were predictive of worst survival.

Keyphrases

poor prognosis
squamous cell carcinoma
end stage renal disease
long non coding rna
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes
lymph node metastasis
locally advanced