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Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?

Zyrafete KuçiNatascha PiedeKathrin VogelsangLisa-Marie PfeffermannSibylle WehnerEmilia Salzmann-ManriqueMiriam StaisHermann KreyenbergHalvard BonigPeter BaderSelim Kuçi
Published in: Journal of translational medicine (2024)
Irrespective of HLA-DR expression at the population level, all MSC preparations significantly inhibited the proliferation of stimulated peripheral blood mononuclear cells, indicating that HLA-DR represents an obsolete release marker for the clinical use of MSCs.
Keyphrases
  • poor prognosis
  • editorial comment
  • mesenchymal stem cells
  • bone marrow
  • signaling pathway