Therapeutic Treatment with Abdominal Adipose Mesenchymal Cells Does Not Prevent Elastase-Induced Emphysema in Rats.
Pinar Yıldız GülhanMehmet Savaş EkiciMehmet NiyazMuhammet GülhanMustafa Emre ErçinAydanur EkiciNurkan AksoyPublished in: Turkish thoracic journal (2020)
Our findings suggest that therapeutic treatment with adipose tissue-derived MSC in rats has no effect on emphysema or on MMP9 expression, which is a known marker of emphysema.
Keyphrases
- adipose tissue
- chronic obstructive pulmonary disease
- lung function
- poor prognosis
- idiopathic pulmonary fibrosis
- insulin resistance
- stem cells
- pulmonary fibrosis
- bone marrow
- high fat diet
- type diabetes
- endothelial cells
- oxidative stress
- skeletal muscle
- combination therapy
- long non coding rna
- diabetic rats
- binding protein
- cystic fibrosis