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Vaginal misoprostol versus vaginal dinoprostone for cervical ripening and induction of labour: An individual participant data meta-analysis of randomised controlled trials.

Malitha PatabendigeFei ChanChristophe VayssiereVirginie EhlingerNicolette Van GemundSaskia le CessieMartina PragerLena MarionsPatrick RozenbergSylvie ChevretDavid C YoungPaul A Le RouxSarah GregsonMark WaterstoneDaniel Lorber RolnikBen-Willem J MolWentao Li
Published in: BJOG : an international journal of obstetrics and gynaecology (2024)
Low-dose vaginal misoprostol and vaginal dinoprostone for IOL are comparable in terms of effectiveness and perinatal safety. However, low-dose vaginal misoprostol is likely to lead to a lower rate of composite adverse maternal outcomes than vaginal dinoprostone.
Keyphrases
  • low dose
  • randomized controlled trial
  • systematic review
  • emergency department
  • pregnant women
  • type diabetes
  • body mass index
  • physical activity
  • weight loss
  • electronic health record
  • birth weight