Intravenous MELAtonin for prevention of Postoperative Agitation and Emergence Delirium in children (MELA-PAED): A protocol and statistical analysis plan for a randomized clinical trial.
Anne Louise de Barros GarioudLars Peter Kloster AndersenAksel Karl Georg JensenHien Quoc DoJanus Christian JakobsenLars Broksø HolstLars Simon RasmussenArash AfshariPublished in: Acta anaesthesiologica Scandinavica (2023)
The MELA-PAED trial investigates the efficacy of intravenous intraoperative melatonin for the prevention of emergence agitation in pediatric surgical patients. Results may provide further knowledge concerning the use of melatonin in pediatric perioperative care.