Predictive value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography for PD-L1 expression in non-small cell lung cancer: A systematic review and meta-analysis.
Hee Yun SeolYun Seong KimSeong-Jang KimPublished in: Thoracic cancer (2020)
Significant findings of the study The current meta-analysis showed a moderate sensitivity and specificity of 18F-FDG PET/CT for the prediction of PD-L1 expression in NSCLC patients. The DOR was low and the likelihood ratio scattergram indicated that 18F-FDG PET/CT might not be useful for the prediction of PD-L1 expression in NSCLC patients and not for its exclusion. What this study adds This study concluded that the role of 18F-FDG PET/CT in predicting tumor expression of PD-L1 should be further elucidated.
Keyphrases
- positron emission tomography
- computed tomography
- end stage renal disease
- newly diagnosed
- small cell lung cancer
- systematic review
- magnetic resonance imaging
- peritoneal dialysis
- prognostic factors
- pet ct
- randomized controlled trial
- advanced non small cell lung cancer
- patient reported outcomes
- long non coding rna
- patient reported
- contrast enhanced
- image quality
- epidermal growth factor receptor
- structural basis