Randomized controlled double-blind trial of methylprednisolone versus placebo in patients with post-COVID-19 syndrome and cognitive deficits: study protocol of the post-corona-virus immune treatment (PoCoVIT) trial.

Christiana FrankeVanessa RaederFabian BoeslBenno BremerLucas C AdamAmeli GerhardIrina EckertAnneke QuitschauAnne PohrtSusen BurockLisa BruckertCarmen ScheibenbogenHarald PrüßHeinrich J Audebert

Published in: Neurological research and practice (2024)

This trial aims to contribute novel evidence for treating patients with PCS, with a primary focus on those manifesting cognitive deficits. By doing so, it may enhance comprehension of the underlying pathophysiological mechanisms, thereby facilitating biomarker research to advance our understanding and treatment of patients with PCS.

Keyphrases

phase iii
study protocol
double blind
placebo controlled
phase ii
clinical trial
open label
randomized controlled trial
sars cov
coronavirus disease
high dose
combination therapy