Myocardial extracellular volume quantification by computed tomography predicts outcomes in patients with severe aortic stenosis.
Yoav HammerYeela Talmor-BarkanAryeh AbelowKatia OrvinYaron AvivNoam BarAmos LeviUri LandesGideon ShafirAlon BarsheshetHana Vaknin-AssaAlexander SagieRan KornowskiAshraf HamdanPublished in: PloS one (2021)
In patients with severe aortic stenosis undergoing computed tomography before aortic valve intervention, quantification of extracellular volume fraction correlated with functional status and markers of left ventricular decompensation, and predicted the 12-months composite adverse clinical outcomes. Implementation of this novel technique might aid in the risk stratification process before aortic valve interventions.
Keyphrases
- aortic stenosis
- aortic valve
- computed tomography
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- left ventricular
- positron emission tomography
- early onset
- randomized controlled trial
- magnetic resonance imaging
- primary care
- healthcare
- ejection fraction
- contrast enhanced
- dual energy
- physical activity
- heart failure
- type diabetes
- image quality
- quality improvement
- emergency department
- mitral valve
- adipose tissue
- hypertrophic cardiomyopathy
- magnetic resonance
- left atrial
- acute myocardial infarction
- cardiac resynchronization therapy
- insulin resistance
- weight loss
- glycemic control