Single Cell Analysis of Human Colonoids Exposed to Uranium-Bearing Dust.

Roger AtangaLidia L AppellMyranda N ThompsonFredine T LauerAdrian BrearleyMatthew J CampenEliseo F CastilloJulie G In

Published in: Environmental health perspectives (2024)

These findings highlight the significance of crypt-based proliferative cells and secretory cell differentiation using human colonoids to model major colonic responses to uranium-bearing particulate dust exposure. https://doi.org/10.1289/EHP13855.

Keyphrases

endothelial cells
single cell
induced pluripotent stem cells
induced apoptosis
pluripotent stem cells
health risk assessment
health risk
polycyclic aromatic hydrocarbons
risk assessment
endoplasmic reticulum stress
cell death
ulcerative colitis
pi k akt