Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry.
Bingxin YangSheng WangWen MaGuanlin LiMengling TuZhiyong MaQinghe ZhangHongmei LiXianjiang LiPublished in: Foods (Basel, Switzerland) (2023)
Dehydrated vegetables are popular in instant foods, but few reports have focused on their pesticide residues. This research developed and validated a modified QuEChERS method combined with ultra-performance liquid chromatography-tandem mass spectrometry to determine 19 kinds of neonicotinoid and carbamate pesticides in freeze-dried cabbage. Herein, acetonitrile/water ( v/v = 2:1) was selected in the extraction step. Meanwhile, 4 g anhydrous magnesium sulfate and 1 g sodium chloride were applied to the partitioning step. Dispersive solid-phase extraction sorbents were selected, and liquid chromatography conditions were further optimized for dealing with the matrix effect. The limits of quantification ranged from 1.0 to 10.0 μg/kg. The validation results were acceptable, with average recoveries of 78.7-114.0% and relative standard deviations below 14.2%. The method recoveries were closely related to the volume proportion of water in the extractant. Finally, the developed method was applied to real freeze-dried cabbages and four pesticides (propamocarb, imidacloprid, acetamiprid, and thiacloprid) were detected in six samples.
Keyphrases
- liquid chromatography tandem mass spectrometry
- solid phase extraction
- simultaneous determination
- gas chromatography
- tandem mass spectrometry
- liquid chromatography
- high performance liquid chromatography
- ultra high performance liquid chromatography
- molecularly imprinted
- risk assessment
- high resolution mass spectrometry
- gas chromatography mass spectrometry
- mass spectrometry
- high resolution
- emergency department
- adverse drug
- heavy metals