Can a specific biobehavioral-based therapeutic education program lead to changes in pain perception and brain plasticity biomarkers in chronic pain patients? A study protocol for a randomized clinical trial.
Silvia Di BonaventuraJosué Fernández CarneroRaúl Ferrer-PeñaPublished in: PloS one (2024)
By comprehensively addressing the need to quantify brain changes more precisely in individuals with chronic pain during interventions like TE and recognizing the importance of establishing a more structured and comprehensive protocol, this study lays a solid and replicable foundation for future evidence-based treatment developments.
Keyphrases
- chronic pain
- pain management
- end stage renal disease
- resting state
- white matter
- quality improvement
- newly diagnosed
- ejection fraction
- healthcare
- chronic kidney disease
- randomized controlled trial
- physical activity
- functional connectivity
- prognostic factors
- spinal cord
- neuropathic pain
- blood brain barrier
- combination therapy