Screening for early onset neonatal sepsis: NICE guidance-based practice versus projected application of the Kaiser Permanente sepsis risk calculator in the UK population.

Nitin GoelSudeep ShresthaRhian SmithAkshay MehtaMalini KettyHelen MuxworthyArtur AbelianVickness KirupaalarShakir SaeedShikha JainAmar AsokkumarMurali NattiIan BarnardPrem Kumar PitchaikaniSujoy Banerjee

Published in: Archives of disease in childhood. Fetal and neonatal edition (2019)

The judicious adoption of SRC in UK clinical practice for screening and management of EONS could potentially reduce interventions and antibiotic usage in three out of four term or near-term infants and promote earlier discharge from hospital in >50%. We did not identify any EONS case missed by SRC when compared with NICE. These results have significant implications for healthcare resources.

Keyphrases

early onset
healthcare
clinical practice
late onset
acute kidney injury
preterm infants
tyrosine kinase
intensive care unit
septic shock
gestational age
primary care
cross sectional
electronic health record
quality improvement
adverse drug
health information
preterm birth