Login / Signup

A Potential Role of Semaphorin 3A during Orthodontic Tooth Movement.

Sinan ŞenChristopher J LuxRalf Erber
Published in: International journal of molecular sciences (2021)
Sema3A, its receptors and Osterix are regulated by mechanical forces in hPDLF. SEMA3A upregulation was associated with Osterix (SP7) modulation. Sema3A-enhanced osteogenic marker gene expression in hOB might be dependent on a pathway involving Rac1GTPase and β-catenin. Thus, Semaphorin 3A might contribute to bone remodeling during induced tooth movement.
Keyphrases