Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2.

Chiara Moltrasio Rachele Cagliani Manuela Sironi Mario Salvatore ClericiChiara PontremoliCarlo Alberto Maronese Paola Maura Tricarico Sergio Crovella Angelo Valerio Marzano

Published in: Vaccines (2023)

Our data suggest that this variant might play a role in susceptibility to develop syndromic forms of HS but not to progress to sporadic HS and PG. Furthermore, epigenetic and/or somatic variations could affect AIM2 expression leading to different, context-dependent responses.

Keyphrases

hidradenitis suppurativa
intellectual disability
poor prognosis
dna methylation
late onset
electronic health record
gene expression
autism spectrum disorder
big data
copy number
binding protein
amyotrophic lateral sclerosis
early onset
data analysis