A randomised phase II study of extended pleurectomy/decortication (e-PD) preceded or followed by chemotherapy in patients (pts) with early-stage pleural mesothelioma (PM): EORTC 1205.
Jo RaskinVeerle SurmontAlexander P W M MaatMaha YahiaSjaak A BurgersYassin PretzenbacherFrederic De RyckRobin CornelissenHouke M KlompAna OliveiraJoachim AertsPaul BaasSandrine MarreaudJan P Van MeerbeeckPaul E Y Van SchilPublished in: The European respiratory journal (2024)
EORTC 1205 did not succeed in selecting a preferred sequence of pre- or postoperative chemotherapy. Either procedure is feasible with a low mortality, albeit consistent morbidity. A shared informed decision between surgeon and patient remains essential.
Keyphrases
- phase ii study
- locally advanced
- early stage
- open label
- end stage renal disease
- clinical trial
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- rectal cancer
- case report
- patients undergoing
- prognostic factors
- type diabetes
- cardiovascular events
- randomized controlled trial
- neoadjuvant chemotherapy
- cardiovascular disease
- polycyclic aromatic hydrocarbons
- coronary artery disease
- patient reported outcomes
- robot assisted
- double blind
- lymph node
- patient reported