Prognostic impact of MUC1 and potential regulatory miR-145 and miR-21 expression in salivary mucoepidermoid carcinoma.
Ali AbdolrahmaniNeda Kardouni KhoozestaniFarid Azmoudeh-ArdalanAhmad Reza ShamshiriPublished in: Head and neck pathology (2022)
Our results support the tumor suppressor role of miR-145 and the oncogenic role of miR-21 in salivary gland MEC. Also, MUC1 and miR-145 overexpression, as well as miR-21 suppression, show promising association with histologic tumor grade and clinical stage.