Hydrochlorothiazide and Prevention of Kidney-Stone Recurrence.
Nasser A DhayatOlivier BonnyBeat RothAndreas ChristeAlexander RitterNilufar MohebbiNicolas FallerLisa PellegriniGiulia BedinoReto M VenzinPhilipp GrosseCarina HüslerIrene KonethChristian BucherRosaria Del GiornoLuca GabuttiMichael MayrUrs OdermattFlorian BuchkremerThomas ErnandezCatherine Stoermann-ChopardDaniel TetaBruno VogtMarie RoumetLuca TamòGrazia M CereghettiSven TrelleDaniel G FusterPublished in: The New England journal of medicine (2023)
Among patients with recurrent kidney stones, the incidence of recurrence did not appear to differ substantially among patients receiving hydrochlorothiazide once daily at a dose of 12.5 mg, 25 mg, or 50 mg or placebo once daily. (Funded by the Swiss National Science Foundation and Inselspital; NOSTONE ClinicalTrials.gov number, NCT03057431.).