Hormonal aggressiveness according to the expression of cellular markers in corticotroph adenomas.

Jung Soo LimMi-Kyung LeeEunhee ChoiNamki HongSoo Il JeeSun Ho KimEun Jig Lee

Published in: Endocrine (2018)

Although PTTG1 and Ki-67 play an essential role in developing ACTH-secreting tumors, cyclin D1, p27, and Brg1 may be better biomarkers to determine hormonal aggressiveness of the tumor. Further research is needed to understand the influence of cellular markers on hormonal activity in CD.

Keyphrases

polycystic ovary syndrome
poor prognosis
cell cycle
insulin resistance
type diabetes
squamous cell carcinoma
signaling pathway
cell proliferation
lymph node
cell cycle arrest
rectal cancer
pi k akt