Aromatic L-Amino Acid Decarboxylase Gene Therapy Enhances Levodopa Response in Parkinson's Disease.
John G NuttCarolin CurtzeAmie HillerShannon AndersonPaul S LarsonAmber D Van LaarR Mark RichardsonMarin E ThompsonAlexander SedkovMika LeinonenBernard RavinaKrystof S BankiewiczChadwick W ChristinePublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
VY-AADC01 improved motor responses to intravenous levodopa given under controlled conditions. These data and findings from the parent study support further clinical development of AADC gene therapy for people with Parkinson's disease. © 2020 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.