The Persistence of Hepatitis C Virus Infection in Hepatocytes Promotes Hepatocellular Carcinoma Progression by Pro-Inflammatory Interluekin-8 Expression.
Ciniso Sylvester ShabanguPhumelele Yvonne SiphephoChia-Yang LiWei-Chung ChengMing-Ying LuChung-Feng HuangMing-Lun YehChia-Yen DaiJee-Fu HuangWan-Long ChuangZu-Yau LinMing-Lung YuShu-Chi WangPublished in: Biomedicines (2021)
Persistent infection with HCV induced pro-inflammatory CXCL8 and the oncogene SRC, thereby triggering and promoting hepatocarcinogenesis. CXCL8 may be a potential biomarker for monitoring HCV-related HCC progression.