ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes.

Anja SoldanCorinne PettigrewAnne M FaganSuzanne E SchindlerAbhay MoghekarChristopher FowlerQiao-Xin LiSteven J CollinsCynthia CarlssonSanjay AsthanaColin L MastersSterling JohnsonJohn C MorrisMarilyn AlbertAlden L Gross

Published in: Neurology (2019)

The results are consistent with the hypothesis that both elevated brain amyloid and neurofibrillary tangles are necessary to observe accelerated neurodegeneration, which in turn leads to cognitive decline.

Keyphrases

cognitive decline
mild cognitive impairment
white matter
resting state
fluorescent probe
living cells
sensitive detection
cross sectional
type diabetes