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Impact of primary tumor sidedness and sex on prognosis and anti-epidermal growth factor receptor antibody efficacy in BRAF-mutant metastatic colorectal cancer: a pooled analysis of AIO studies FIRE-1, CIOX, FIRE-3, XELAVIRI, and VOLFI.

A H S AligD P ModestS StintzingK HeinrichM GeisslerL Fischer von WeikersthalT DeckerU Vehling-KaiserS HeldN MoosmannA StahlerA TannapfelC Giessen-JungA JungL WeissV Heinemann
Published in: ESMO open (2024)
This analysis suggests that PTS has predictive value for the efficacy of anti-EGFR mAb in the first-line treatment of BRAFmt mCRC.
Keyphrases
  • epidermal growth factor receptor
  • metastatic colorectal cancer
  • tyrosine kinase
  • advanced non small cell lung cancer
  • small cell lung cancer
  • wild type
  • randomized controlled trial
  • open label
  • double blind