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simplePHENOTYPES: SIMulation of pleiotropic, linked and epistatic phenotypes.

Samuel B FernandesAlexander E Lipka
Published in: BMC bioinformatics (2020)
simplePHENOTYPES is a R/CRAN package that makes it possible to simulate multiple traits controlled by loci with varying degrees of pleiotropy. Its ability to interface with both commonly-used marker data formats and downstream quantitative genetics software and packages should facilitate a rigorous assessment of both existing and emerging statistical GWAS and GS approaches. simplePHENOTYPES is also available at https://github.com/samuelbfernandes/simplePHENOTYPES .
Keyphrases
  • genome wide
  • genome wide association study
  • data analysis
  • electronic health record
  • high resolution
  • dna methylation
  • genome wide association
  • clinical evaluation