Polar lipids modify Alzheimer's Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation.
Sakshi HansJanelle E StantonAnn Katrin SauerKatie ShielsSushanta Kumar SahaRonan LordanAlexandros B TsouprasIoannis ZabetakisAndreas Martin GrabruckerPublished in: Lipids in health and disease (2024)
Our results highlight a novel underlying mechanism, why consuming PL-rich foods such as fish and dairy may reduce the risk of developing dementia and associated disorders.