Chronic kidney disease and physiologically based pharmacokinetic modeling: a critical review of existing models.

Ammara ZamirFaleh AlqahtaniMuhammad Fawad Rasool

Published in: Expert opinion on drug metabolism & toxicology (2024)

This review will provide insights for researchers on applying PBPK models in managing patients with different levels of CKD to prevent undesirable side effects and increase the effectiveness of drug therapy.

Keyphrases

chronic kidney disease
end stage renal disease
randomized controlled trial
systematic review
adverse drug
bone marrow
mesenchymal stem cells
electronic health record
smoking cessation