Long non-coding RNA SNHG5 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the miR-212-3p/GDF5/SMAD pathway.

Yineng HanQiaolin YangYiping HuangLingfei JiaYunfei ZhengWeiran Li

Published in: Stem cell research & therapy (2022)

Our results demonstrated that the novel pathway YY1/SNHG5/miR-212-3p/GDF5/Smad regulates osteogenic differentiation of hBMSCs and may serve as a potential target for the treatment of bone loss.

Keyphrases

long non coding rna
poor prognosis
bone loss
epithelial mesenchymal transition
transforming growth factor
risk assessment
combination therapy