Immune checkpoint expression in HNSCC patients before and after definitive chemoradiotherapy.

Johannes DoescherPeter MinkenbergSimon LabanUlrike KostezkaAdrian von WitzlebenThomas Karl HoffmannPatrick Johannes SchulerStephanie Ellen Weissinger

Published in: Head & neck (2020)

Conventional CRT changes the expression of CD27 in the tumor microenvironment. Whether this is due to a loss of expression or a reduction of CD27+ cells must be evaluated in further analyses.

Keyphrases

poor prognosis
end stage renal disease
binding protein
ejection fraction
induced apoptosis
long non coding rna
prognostic factors
heart failure
cell cycle arrest
signaling pathway
oxidative stress
radiation therapy
cell death