The influence of proton pump inhibitor therapy on the outcome of infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies.
Thomas X LuMatthew DapasErika LinTrevor PetersAtsushi SakurabaPublished in: Gut (2020)
In this patient-level meta-analysis of randomised controlled studies, we found that patients with IBD taking PPI were less likely to achieve remission while on infliximab therapy. The results of our study warrant further investigation into the effect of PPI on IBD outcomes and therapies.
Keyphrases
- systematic review
- case control
- ulcerative colitis
- case report
- meta analyses
- study protocol
- randomized controlled trial
- stem cells
- rheumatoid arthritis
- clinical trial
- mesenchymal stem cells
- systemic lupus erythematosus
- small molecule
- disease activity
- insulin resistance
- smoking cessation
- weight loss
- double blind
- glycemic control