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Choline supplementation in children with fetal alcohol spectrum disorders: a randomized, double-blind, placebo-controlled trial.

Jeffrey R WozniakAnita J FuglestadJudith K EckerleBirgit A FinkHeather L HoeckerChristopher J BoysJoshua P RadkeMaria G KroupinaNeely C MillerAnn M BrearleySteven H ZeiselMichael K Georgieff
Published in: The American journal of clinical nutrition (2015)
This pilot study suggests that an additional evaluation of choline supplementation as an intervention for memory functioning in children with FASDs is warranted. The observed interaction between age and choline's effect on EI suggests that potential sensitive periods should be considered in future work. This trial was registered at clinicaltrials.gov as NCT01149538.
Keyphrases
  • double blind
  • study protocol
  • young adults
  • clinical trial
  • randomized controlled trial
  • phase iii
  • placebo controlled
  • phase ii
  • alcohol consumption
  • climate change