Idiopathic pulmonary fibrosis: pathogenesis and management.
Giacomo SgallaBruno IoveneMariarosaria CalvelloMargherita OriFrancesco VaroneLuca RicheldiPublished in: Respiratory research (2018)
Building on the advances in the understanding of IPF pathobiology, the further investigation of the role of gene variants, epigenetic alterations and other molecular biomarkers reflecting disease activity and behaviour will hopefully enable earlier and more confident diagnosis, improve disease phenotyping and support the development of novel agents for personalized treatment of IPF.
Keyphrases
- idiopathic pulmonary fibrosis
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- copy number
- interstitial lung disease
- ankylosing spondylitis
- juvenile idiopathic arthritis
- gene expression
- dna methylation
- high throughput
- combination therapy
- single cell
- transcription factor
- genome wide identification