PAciFy Cough-a multicentre, double-blind, placebo-controlled, crossover trial of morphine sulphate for the treatment of pulmonary Fibrosis Cough.
Zhe WuWinston BanyaNazia ChaudhuriIra JakupovicToby M MaherBrijesh PatelLisa G SpencerMuhunthan ThillaiAlex WestJohn WestobyMarlies WijsenbeekJaclyn SmithPhilip L MolyneauxPublished in: Trials (2022)
The study was approved by the UK Medicines and Healthcare Regulatory Agency (Ref: CTA 21268/0224/001-0001 - EUDRACT 2019-003571-19 - Protocol Number RBH2019/001) on 08 April 2020, in compliance with the European Clinical Trials Directive and the Medicines for Human Use (Clinical Trials) Regulations 2004 and its subsequent amendments. The study was provided with ethical approval by the London Brent Research Ethics Committee (Ref: 20/LO/0368) on 21 May 2020 and is registered with clinicaltrials.gov (NCT04429516) on 12 June 2020, available at https://clinicaltrials.gov/ct2/show/NCT04429516.
Keyphrases
- clinical trial
- double blind
- placebo controlled
- phase ii
- phase iii
- healthcare
- study protocol
- open label
- randomized controlled trial
- pulmonary fibrosis
- computed tomography
- endothelial cells
- transcription factor
- squamous cell carcinoma
- magnetic resonance imaging
- pet ct
- magnetic resonance
- social media
- phase ii study
- induced pluripotent stem cells
- contrast enhanced
- deep learning
- health information