A Protocol To Transform Sulfones into Nitrones and Aldehydes.

Eduardo RodrigoInés AlonsoMaría Belén Cid

Published in: Organic letters (2018)

A simple method to transform sulfones into nitrones and therefore into the corresponding carbonyl derivatives has been developed. Some examples demonstrate that it is a new reliable and versatile reaction in the toolbox of sulfones that has great synthetic potential. NMR and computational studies were used to elucidate the mechanism.

Keyphrases

magnetic resonance
randomized controlled trial
high resolution
case control
solid state
mass spectrometry
risk assessment