Roseburia hominis Alleviates Neuroinflammation via Short-Chain Fatty Acids through Histone Deacetylase Inhibition.
Lijin SongQinghua SunHaonan ZhengYiming ZhangYujing WangShuangjiang LiuLi Ping DuanPublished in: Molecular nutrition & food research (2022)
These findings suggest that R. hominis alleviates neuroinflammation by producing propionate and butyrate, which serve as HDAC inhibitors. This study provides a potential psychoprobiotic to reduce neuroinflammation.