Exploring Anticancer and (Bio)catalytic Activities of New Oxovanadium(V), Dioxomolybdenum(VI), and Copper(II) Complexes of Amide-Imine Conjugates.
Sabyasachi TaMilan GhoshKajari GhoshPaula BrandãoVítor FélixSumit Kumar HiraPartha Pratim MannaDebasis DasPublished in: ACS applied bio materials (2019)
An amide-imine conjugate, ( E )- N '-((2-hydroxynaphthalen-1-yl) methylene)-4-methylbenzohydrazide (PTANAP), derived from 4-methyl-benzoic acid hydrazide (PTA) and 2-hydroxynapthaldehyde, is explored to prepare dinuclear oxovanadium(V), mononuclear dioxomolydenum(VI), and Cu(II) complexes. Single crystal X-ray structurally characterized complexes have been exploited as catalyst for oxidation of ethylbenzene, catechol, and o -aminophenol. The anticancer properties of the oxo-vanadium complex have been explored against human leukemia cell (K-562) and mouse lymphoma cells (2PK3).
Keyphrases
- induced apoptosis
- endothelial cells
- cancer therapy
- single cell
- cell cycle arrest
- acute myeloid leukemia
- bone marrow
- diffuse large b cell lymphoma
- high resolution
- ionic liquid
- room temperature
- metal organic framework
- peripheral blood
- magnetic resonance imaging
- endoplasmic reticulum stress
- highly efficient
- magnetic resonance
- cell proliferation
- oxidative stress
- pluripotent stem cells
- carbon dioxide
- cell death
- gold nanoparticles
- pi k akt
- contrast enhanced