Digital quantification of somatostatin receptor subtype 2a immunostaining: a validation study.
Claudia CampanaPeter M van KoetsveldRichard A FeeldersWouter W de HerderAnand M IyerMarie-Louise F van VelthuysenMarije J VeenstraElisabeth S R van den DungenSanne E FranckDiego FeroneFederico GattoLeo J HoflandPublished in: European journal of endocrinology (2022)
The DIA has an excellent inter-observer agreement and showed a strong correlation with the widely used semi-quantitative IRS. The DIA protocol is an open-source, highly reproducible tool and provides a reliable quantitative evaluation of SST2 immunohistochemistry.