Protective effect of tert -butylhydroquinone against cisplatin-induced hepatorenal injury via modulating oxidative stress, inflammation, and apoptosis.

Godwin Adakole UjahEmmanuel Oleba OfutetCatherine Ironya-Ogar UkamPrecious Evangeline OmiunuEmaediong Ufot AckleyIboro Godwin JaphetJane Charles NtaukoQueen Comfort ClementRacheal AtuVictor Udo Nna

Published in: Archives of physiology and biochemistry (2024)

Pre-intervention with tBHQ attenuates hepatorenal toxicity of CDDP by dampening oxidative stress, inflammation and apoptosis.

Keyphrases

oxidative stress
diabetic rats
dna damage
ischemia reperfusion injury
induced apoptosis
randomized controlled trial
signaling pathway
endoplasmic reticulum stress
cell death
heat stress