Effects of exenatide and open-label SGLT2 inhibitor treatment, given in parallel or sequentially, on mortality and cardiovascular and renal outcomes in type 2 diabetes: insights from the EXSCEL trial.
Lindsay E CleggRobert C PenlandSrinivas BachinaDavid W BoultonMarcus ThuressonHiddo J L HeerspinkStephanie GustavsonC David SjöströmJames A RugglesAdrian F HernandezJohn B BuseRobert J MentzRury R HolmanPublished in: Cardiovascular diabetology (2019)
This post hoc analysis supports the hypothesis that combinatorial EQW and SGLT2i therapy may provide benefit on cardiovascular outcomes and mortality. Trial registration Clinicaltrials.gov, Identifying number: NCT01144338, Date of registration: June 15, 2010.
Keyphrases
- phase iii
- open label
- phase ii
- study protocol
- type diabetes
- clinical trial
- cardiovascular events
- risk factors
- glycemic control
- randomized controlled trial
- cardiovascular disease
- phase ii study
- combination therapy
- coronary artery disease
- squamous cell carcinoma
- adipose tissue
- stem cells
- mesenchymal stem cells
- weight loss