NXPH4 mediated by m 5 C contributes to the malignant characteristics of colorectal cancer via inhibiting HIF1A degradation.

Lei YangJiawen ShiMingyang ZhongPingping SunXiaojing ZhangZhengyi LianHang YinLijun XuGuyin HeHaiyan XuHan WuZiheng WangKai MiaoJianfei Huang

Published in: Cellular & molecular biology letters (2024)

C, promotes malignant tumor progression and regulates the HIF pathway. Consequently, targeting NXPH4 through molecular therapies could potentially serve as an efficacious therapeutic strategy for the management of CRC exhibiting elevated NXPH4 expression.

Keyphrases

poor prognosis
endothelial cells
long non coding rna
signaling pathway
cancer therapy
binding protein
single molecule