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Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score.

Aaron P ThriftFasiha KanwalYanhong LiuSaira KhaderiAmit G SingalJorge A MarreroNicole LooSumeet K AsraniMichelle LusterAbeer Al-SarrajJing NingSpiridon TsavachidisXiangjun GuChristopher I AmosHashem B El-Serag
Published in: PloS one (2023)
Our findings suggest that PRS may enhance risk prediction for HCC in contemporary U.S. cirrhosis patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • adipose tissue
  • papillary thyroid
  • prognostic factors
  • fatty acid
  • young adults