Aortic Injury Induced by Benzo(a)pyrene and Atherogenic Diet Increased Hepatic FGF21 Expression in C57BL/6J Mice.

Farzane Shanehbandpour-Tabari Fatemeh Gholamnataj Nahid Neamati Ebrahim Zabihi Farideh Feizi Hadi Parsian

Published in: Iranian journal of pharmaceutical research : IJPR (2024)

Our findings revealed that BaP increases the expression of endogenous FGF21 in treated animals as a compensatory response to protect the heart from atherosclerosis induced by BaP and AtD.

Keyphrases

poor prognosis
cardiovascular disease
heart failure
binding protein
left ventricular
type diabetes
high fat diet induced
newly diagnosed
low density lipoprotein