Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis.
Vladimir KuklinMichael SovershaevJohan BjernerPhilip KeithL Keith ScottOwen Matthew Truscott ThomasWladimir SzpirtGail RockBernd StegmayrPublished in: Critical care (London, England) (2024)
Our comprehensive and up-to-date review demonstrates that adjunct TPE may provide potential survival benefits when compared to standard care for critically ill adult patients with sepsis-induced organ dysfunction. While results of this meta-analysis are encouraging, large well-designed randomized trials are required to identify the optimal patient population and TPE procedure characteristics prior to widespread adoption into practice.
Keyphrases
- systematic review
- diabetic rats
- high glucose
- healthcare
- oxidative stress
- acute kidney injury
- intensive care unit
- septic shock
- primary care
- quality improvement
- palliative care
- drug induced
- randomized controlled trial
- cardiovascular disease
- cardiovascular events
- meta analyses
- risk factors
- type diabetes
- electronic health record
- risk assessment
- pain management
- case control