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Mesenchymal stromal cell conditioned media for lung disease: a systematic review and meta-analysis of preclinical studies.

Chimobi EmukahEvan DittmarRija NaqviJohn MartinezAlexis CorralAxel MoreiraAlvaro G Moreira
Published in: Respiratory research (2019)
In this meta-analysis of animal models recapitulating lung disease, CdM improved inflammation and had an effect size comparable to MSCs. While these findings are encouraging, the risk of bias and heterogeneity limited the strength of our findings.
Keyphrases
  • systematic review
  • single cell
  • bone marrow
  • case control
  • cell therapy
  • mesenchymal stem cells
  • oxidative stress
  • stem cells
  • meta analyses
  • randomized controlled trial
  • umbilical cord